A new approach for cellular immunotherapy of nasopharyngeal carcinoma
نویسندگان
چکیده
Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated malignancy that is highly prevalent in Southern China and South-East Asia. EBV-targeted immunotherapy remains a goal in the development of novel treatment strategies. A novel adenoviral polyepitope-based immunotherapy has been developed to rapidly generate high frequency EBV-specific T cells to treat patients with refractory or metastatic disease.
منابع مشابه
In vivo and in vitro studies of immunotherapy of nasopharyngeal carcinoma with transfer factor.
Epstein-Barr virus, the apparent cause of infectious mononucleosis, may also be an etiological agent in nasopharyngeal carcinoma and Burkitt's lymphoma. Lymphocytes from normal individuals with anti-Epstein-Barr virus antibody activity may be sensitized to Epstein-Barr virus and contain transfer factor with the potential to program and/or recruit other lymphocytes to react against the virus and...
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2012